Reinoud Van Mechelen completed his singing studies at the Royal Conservatory of Brussels in 2012 in the class of Dina Grossberger. In 2017 he was awarded the Caecilia Prize as “Young Musician of the Year” by the Union of Belgian Composers. Since 2011 he has been a member of William Christie and Paul Agnew's "Le Jardin des Voix", after which he became a regular soloist at "Les Arts Florissants". He collaborates with baroque ensembles such as Collegium Vocale Gent, Le Concert Spirituel, Le Concert d'Astrée, Les Talens Lyriques, Pygmalion, Le Poème Harmonique, B'Rock, Ricercar Consort, Scherzi Musicali, Hespèrion XXI and performs in the most prestigious concert halls on. Among his recent and future projects: Orphée in Gluck's Orphée et Eurydice (Paris version) at the Philharmonie de Paris with Les Arts Florissants Les Boréades (Abaris) for a European tour, Jason Médée at the Opéra national de Paris and at the Teatro Real in Madrid, Aty's title role with Les Talens lyriques in Versailles and in Vienna.

His discography includes, among many other recordings, six solo albums on Alpha Classics together with the Ensemble a nocte temporis that he founded himself: Erbame Dich (2016), Clérambault, cantates françaises (2018), The Dubhlinn Gardens (Irish folk-songs, 2019), Dumesny, haute-contre de Lully (2019), Jéliote, haute-contre de Rameau (2021) and Legros, haute-contre de Gluck (2023).